Jong PSV vs TelstarNetherlands Eerste Divisie18 October 2021
Volendam vs BredaNetherlands Eerste Divisie18 October 2021
Jong Utrecht vs RodaNetherlands Eerste Divisie18 October 2021
Jong AZ vs Young AjaxNetherlands Eerste Divisie18 October 2021
Twente vs Willem IINetherlands Eredivisie17 October 2021
NEC vs VitesseNetherlands Eredivisie17 October 2021
Sparta vs GroningenNetherlands Eredivisie17 October 2021
AZ Alkmaar vs UtrechtNetherlands Eredivisie17 October 2021